William Nunery, M.D.

William Nunery, M.D.

William Nunery, M.D.
Clinical Associate Professor of Ophthalmology Department of Ophthalmology and Visual Sciences

Director, Oculofacial Plastic & Orbital Surgery Service


Clinical evaluation, diagnosis and treatment of orbital and periorbital trauma and disease processes. These disease processes include aesthetic and reconstructive surgery specializing in the face, orbits, eyelids and lacrimal system, specifically: ophthalmic Graves’ disease, repair of oculofacial/orbital trauma, development and reconstruction of the anophthalmic socket, correction of eyelid malposition, and tearing/lacrimal outflow issues.

301 E. Muhammad Ali Boulevard, Louisville KY 40202
Telephone: 502-852-5466 Fax: 502-852-8550

Case Western Reserve University School of Medicine, Cleveland, Ohio, 1975

Indiana University, Indianapolis, Indiana – 1976-79

Oculofacial Plastic & Orbital Surgery – Emory University, Atlanta, GA -1979-1980

American Board of Ophthalmology, 1980


American Academy of Ophthalmology
American Medical Association
American Society of Ophthalmic Plastic & Reconstructive Surgery
Greater Louisville Medical Society
Kentucky Academy of Eye Physicians and Surgeons

My primary research interests have focused on three main topics in oculofacial plastic and orbital surgery. These include the delineation of subtypes and best treatments for ophthalmic Graves’ disease, the development and rehabilitation of the anophthalmic socket, and reconstruction practices in orbitofacial trauma. Highlights of the Graves’ research include the definition and clinical significance of two subtypes of ophthalmic Graves’ disease, the discovery of the relationship of cigarette smoking to Graves’ disease and the differential impact on subtypes, as well as defining the role of decompression surgery in subtypes of Graves’ disease and its relationship to diplopia. Anophthalmic socket research interests helped to define the role of volume implantation in congenital anophthalmia, demonstrated the effects of radiation on hydroxyapatite use in the orbit, defined mechanical aspects of improved ocular prosthetic motility and investigated the psychological impact of enucleation surgery. Clinical research in oculofacial trauma has included definition of the post face trauma syndrome, and description of multiple surgical techniques which emphasize the role of the orbit in facial trauma reconstruction. These surgical techniques have included the use of nonporous, wraparound implants for medial wall and floor fractures, the lateral canthal approach to trimalar complex fractures, and an open approach to internal fixation of nasal fractures, as well as definition of midline chiasmal injury in naso-orbital fractures

Other current research interests include: a new surgical technique for treatment of blepharospasm, reporting results of autogenous fascial frontalis suspension for use in ptosis repair, describing late pain syndrome following use of hydroxyapatite orbital implantation, and continuing our investigation of pathophysiologic differences in the subtypes of ophthalmic Graves’ disease.

PUBLICATIONS: (15 selected publications from 69)

  1. Nunery WR, Martin RT, Heinz GW, Gavin TJ. The association of cigarette smoking with clinical subtypes of ophthalmic Graves’ disease. Ophthal Plast Reconstr Surg. 1993 Jun;9(2):77-82. PMID: 8323911
  2. Nunery WR, Nunery CW, Martin RT, Truong TV, Osborn DR. The risk of diplopia following orbital floor and medial wall decompression in subtypes of ophthalmic Graves’ disease. Ophthal Plast Reconstr Surg. 1997 Sep;13(3):153-60. PMID: 9306434
  3. Sokol JA, Foulks GN, Haider A, Nunery WR. Ocular surface effects of thyroid disease. Ocul Surf. 2010 Jan;8(1):29-39. PMID: 20105405
  4. Nunery, W.R. Lateral canthal approach to repair of trimalar fractures of the zygoma. Ophthal Plast Reconstr Surg. 1985;1(3):175-83. PMID: 3940128
  5. Heinz GW, Nunery WR, Grossman CB. Traumatic chiasmal syndrome associated with midline basilar skull fractures. Am J Ophthalmol. 1994 Jan 15;117(1):90-6.PMID: 8291599
  6. Nunery WR, Tao JP, Johl S. Nylon foil “wraparound” repair of combined orbital floor and medial wall fractures. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24(4):271-5. PMID: 18645429
  7. Nunery WR, Tao JP. Medial canthal open nasal fracture repair. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24(4):276-9. PMID: 18645430
  8. Lee HBH, Nunery WR. Orbital adherence syndrome secondary to titanium implant material. Ophthal Plast Reconstr Surg. 2009 Jan-Feb;25(1):33-6. PMID: 19273920
  9. Martin RT, Nunery WR, Bonnin JM, Rate WR. Effects of radiation on the use of hydroxyapatite for the orbital reconstruction in the rabbit. Ophthal Plast Reconstr Surg. 1993 Jun;9(2):105-11. PMID: 8391836
  10. Nunery WR, Heinz GW, Bonnin JM, Martin RT, Cepela MA. Exposure rate of hydroxyapatite spheres in the anophthalmic socket: histopathologic correlation and comparison with silicone sphere implants. Ophthalmic Plastic and Reconstructive Surgery. Ophthal Plast Reconstr Surg. 1993 Jun;9(2):96-104. PMID: 8391837
  11. Nunery, WR. Psychological Aspects of Enucleation Surgery. Journal of Ophthalmic Prosthetics, Fall 2002, Volume 7. No.1.
  12. Tao JP, LeBoyer RM, Hetzler K, Ng JD, Nunery WR. Infolateral Migration of Hydrogel Orbital Implants in Microphthalmia. Ophthal Plast Reconstr Surg. 2010 Jan-Feb;26(1):14-7. PMID: 2009047
  13. Nunery, W.R.: Risk of prion transmission with the use of xenografts and allografts in surgery. Ophthal Plast Reconstr Surg. 2001 Nov;17(6):389-94. PMID: 11766016
  14. Sokol JA, Thornton IL, Lee HBH, Nunery WR: Modified Frontalis Suspension Technique With Review of Large Series. Ophthal Plast Reconstr Surg. 2010 Oct 11. [Epub ahead of print] PMID: 20940659
  15. Nunery WR, Welsh MG, McCord CD Jr. Recurrence of sebaceous carcinoma of the eyelid after radiation therapy. Am J Ophthalmol. 1983 Jul;96(1):10-5. PMID: 6869463