Aparna Ramasubramanian, MD

Aparna Ramasubramanian, MD

Aparna Ramasubramanian, MD

Assistant Professor of Ophthalmology

Amblyopia (Lazy Eye), Strabismus (Pediatric & Adult), Diplopia, Nasolacrimal duct Obstruction, Graft versus host disease, Retinoblastoma, Pediatric and Adult eye cancers

301 E. Muhammad Ali Boulevard, Louisville KY 40202
Telephone: 502-852-3386 (office) 502-852-0162 (lab) Fax: 502-852-3588

University of Kerala, India


Post Graduate Institute of Medical Education & Research (PGIMER), India
Drexel University, Philadelphia, PA

Ocular Oncology – Wills Eye Hospital, Philadelphia, PA
Pediatric Ophthalmology and Adult Strabismus – Children’s Hospital Boston, Harvard University, Boston, MA

American Board of Ophthalmology
Indian Board of Ophthalmology

Retinoblastoma – I specialize in treating children with retinoblastoma and am also keenly involved in raising awareness for early detection of the disease. My research interests are in improving treatment outcomes in patients with retinoblastoma

Adult and Pediatric Eye Cancers – I treat adults and children with eye cancers and eye manifestations of systemic cancer. I also treat patients who have eye complications after bone marrow transplantation

Pediatric Ophthalmology – I treat a range of pediatric eye problems including refractive error, amblyopia and strabismus

Adult strabismus – I also treat adults with diplopia (double vision) or strabismus with prisms glasses or surgery (adjustable suture)


  1. Ramasubramanian A, Kytasty C, Meadows AT, Shields JA, Leahy A, Shields CL. Incidence of Pineal gland cyst and pineoblastoma in patients with retinoblastoma during the chemoreduction era. American Journal of Ophthalmology.156(4):825-9,2013.
  2. Ramasubramanian A, Mantagos I, Vanderveen D. Corneal endothelial cell characteristics after pediatric cataract surgery.: J Pediatr Ophthalmol Strabismus.50(4):251-4,2013.
  3. Ramasubramanian A, Correa ZM, Augsburger JJ, Sisk RA, Plager DA.: Medulloepithelioma in DICER1 Syndrome treated with Resection. Eye. 27(7):896-7, 2013.
  4. Ramasubramanian A, Shields CL, Kytasty C, Mahmood Z, Shah SU, Shields JA.: Resection of Intraocular Tumors (Partial Lamellar Sclerouvectomy) in the Pediatric Age Group. Ophthalmology.119:2507-13, 2012.
  5. Ramasubramanian A, Shields CL.: Bevacizumab for Coats Disease with Exudative Retinal Detachment and Risk of Vitreoretinal Traction. Br J Ophthalmol.96:356-9, 2012.
  6. Shields CL, Ramasubramanian A, Mellen PL, Shields JA.: Conjunctival Squamous Cell Carcinoma Arising in Immunosuppressed Patients (Organ Transplant, Human Immunodeficiency Virus Infection). Ophthalmology.118:2133-2137, 2011.
  7. Ramasubramanian A, Shields CL, Mellen PL, Haji S, Harmon SA, Vemuganti GK, Shields JA.: Autofluorescence of Retinoblastoma in 88 Tumors. J AAPOS.15:167-72, 2011.
  8. Shields CL, Bianciotto C, Ramasubramanian A, Lally SE, Jabhour P, Griffin GC, Rosenwasser R, Shields JA.: Intra-arterial chemotherapy for retinoblastoma. Report #1: Control of retinal tumors, vitreous seeds and subretinal seeds. Arch Ophthalmol.129:1399-406, 2011.
  9. Shields CL, Bianciotto C, Jabhour P, Griffin GC, Ramasubramanian A, Rosenwasser R, Shields JA.: Intra-arterial chemotherapy for retinoblastoma. Report #2: Treatment complications. Arch Ophthalmol.129:1407-15, 2011.
  10. Ramasubramanian A, Shields CL, Longmire M, Hunt DJ.: Secondary Choroidal Lymphoma in a Child Treated for Burkitt’s Lymphoma. J AAPOS.15:94-5, 2011.
  11. Shields CL, Ramasubramanian A, Ganguly A, Mohan D, Shields JA.: Cytogenetic testing of iris melanoma using fine needle aspiration biopsy in 17 cases. Retina.31:574-580, 2011.
  12. Vijayakrishnan R, Shields CL, Ramasubramanian A, Emerich J, Rosenwasser R, Shields JA.: Radiation toxicity during intra-arterial chemotherapy for retinoblastoma – should we be concerned? Arch Ophthalmol.128:1427-31, 2010.
  13. Ramasubramanian A, Shields CL, Harmon SA, Shields JA.: Autofluorescence of choroidal hemangioma in 34 consecutive eyes. Retina.30:16-22, 2010.
  14. Ramasubramanian A, Shields CL, Sinha N, Shields JA.: Ocular Surface Squamous Neoplasia after Corneal Graft. Am J Ophthalmol.149:62-5, 2010.
  15. Sinha N, Shields CL, Ramasubramanian A, Ferenczy S, Shields JA.: Giant Spontaneously regressed retinoblastoma. Canadian Journal of Ophthalmology.45:89-90, 2010.
  16. Goodwin P, Shields CL, Ramasubramanian A, Brown GC, Shields JA.: Ranibizumab for coloboma related choroidal neovascular membrane in a child. J AAPOS.13:616-7, 2009.
  17. Shields CL, Ramasubramanian A, Rosenwasser R, Shields JA.: Superselective catheterization of the ophthalmic artery for intraarterial chemotherapy for retinoblastoma. Retina.29:1207-1209, 2009.
  18. Choudhry N, Ramasubramanian A, Shields CL, Brown G, Shields JA.: Spontaneous Resolution of Retinal Detachment in Morning Glory Disc Anomaly. J AAPOS.13(5):499-500, 2009.
  19. Shields CL, Ramasubramanian A, Thangappan A, Hartzell K, Leahey A, Meadows AT, Shields JA.: Group E Retinoblastoma Managed with Chemoreduction Alone Versus Chemoreduction Plus Prophylactic Low Dose External Beam Radiotherapy in 76 Eyes. Ophthalmology.116:544-551, 2009.
  20. Ramasubramanian A, Shields CL, Palamar M, Rousta ST, Shields JA.: Conjunctival Edema and Multiple Eyelash Rows(Congenital Distichiasis) in Association with Congenital Lymphedema of the Lower Legs. Ophthal Plast Reconstr Surg.25:148-50, 2009.
  21. Ichhpujani P, Pandav SS, Ramasubramanian A, Kaushik S.: Bilateral Developmental glaucoma associated with Optic disc pit and uveal effusion. Ophthalmic Surg Lasers Imaging.40:290-292, 2009.
  22. Singh U, Ramasubramanian A, Bal A.: Congenital orbital teratoma presenting as microphthalmos with cyst. Indian Journal of Ophthalmology.57:474-5, 2009.
  23. Nallasamy S, Ramasubramanian A, Shields CL, Tipperman R, Shields JA.: Chemoreduction for non-visualized retinoblastoma hidden behind dense cataract. Canadian Journal of Ophthalmology.57:474-5, 2009.
  24. Shields CL, Palamar M, Sharma P, Ramasubramanian A, Leahey A, Meadows AT, Shields JA. Retinoblastoma Regression Patterns Following Chemoreduction and Adjuvant Therapy in 557 Tumors. Arch Ophthalmol.127(3):282-90, 2009.
  25. Kaushik S, Ichhpujani P, Ramasubramanian A, Pandav SS.: Occult intraocular foreign body: Ultrasound Biomicroscopy holds the key. International Ophthalmology.28:71-73, 2008

BOOKS / CHAPTERS (Selected):

  1. Editor: Ramasubramanian A, Shields CL (Eds.): New Delhi, India., Jaypee Brothers, 2012, 277 pp.
  2. Editor: Ramasubramanian A, Vanderveen DK (Section Editor) Extraocular Muscle Surgery In Ichhpujani P, Spaeth GL, Yanoff M. (Ed.); Expert Techniques in Ophthalmic Surgery. New Delhi, India., Jaypee Brothers, 2015, pp. 841-923.
  3. Author: Ramasubramanian A and Shields CL.: Autofluorescence of Retinoblastoma. In Lois N, Forrester JV (Ed.); Fundus Autofluorescence. Lippincott Williams & Wilkins, 2014.
  4. Author: Ramasubramanian A and Shields CL.: Autofluorescence of Choroidal Hemangioma. In Lois N, Forrester JV (Ed.); Fundus Autofluorescence. Lippincott Williams & Wilkins, 2014.
  5. Author: Ramasubramanian A, Shields CL. Metastatic tumors to the eye and adnexa. In Maguire JI, Murchison AP, Jaeger EA (Ed.); 5 minute consult in ophthalmology. Philadelphia, Lippincott Williams & Wilkins, 2011.
  6. Author: Shields CL, Ramasubramanian A, Harmon Sarah, Lally SE.: RetCam™ Imaging of Pediatric Intraocular Tumors. In Advances in Retinal Imaging (Essentials in Ophthalmology). New York, Springer-Verlag, 2010.